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DNA-based self-sorting of nanoparticles on gold surfaces

DNA-based self-sorting of nanoparticles on gold surfaces
Author:

U. Plutowski, S. S. Jester, S. Lenhert, M. M. Kappes, C. Richert 

links:
Source:

Adv. Mater. 19 (2007) 1951-1956 

Date: 2007

Site-selective deposition of nanoparticles onto surfaces is desirable for the fabrication of nanoscale devices. For nanoparticles with vastly different numbers of DNA chains on their surfaces, multivalent binding of short-sequence motifs and nonspecific adsorption complicate sequence-specific immobilization from mixtures. A new nanoparticle coating method that suppresses salt-induced aggregation and undesirable binding events is reported. Size-selective sorting of gold nanoparticles up to 60 nm diameter onto nanopatterned surfaces is shown (see figure).