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Multi-Color Polymer Pen Lithography for Oligonucleotide Arrays

Multi-Color Polymer Pen Lithography for Oligonucleotide Arrays
Author:

R. Kumar, S. Weigel, R. Meyer, C. M. Niemeyer, H. Fuchs, M. Hirtz

links:
Source:

Chem. Commun. 52 (2016) 12310-12313

Date: 2016

Multi-color patterning by polymer pen lithography (PPL) was used to fabricate covalently immobilized fluorophor- and oligonucleotide arrays with up to five different components. The oligonucleotide arrays offer a virtually unlimited inventory of orthogonal binding tags for self-assembly of proteins as demonstrated by use of the arrays to monitor cell-protein interactions of MCF7 cells.