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Seminar

Chemical and Physical-Chemical Peculiarities of Molecular Container Compounds

Wednesday, 10 August 2016, 13:30-15:00
Institute of Nanotechnology Seminar room 0-167
Talk given by Prof. Werner Nau Life Sciences & Chemistry Jacobs University Bremen Germany Abstract: Molecular container compounds are macrocyclic host molecules, which are sufficiently large to encapsulate in their interior smaller guest molecules. They have taken over a leading position in the development of supramolecular chemistry, because they provide a playground for the detailed investigation of intermolecular interactions. Their inner cavity has even been considered as a “new phase of matter”. We will provide an overview of our research in the area of molecular container compounds, ranging form solvatochromic probes to investigate the microenvironment inside the cavities, their interactions with fluorescent dyes and resulting applications, catalysis inside the cavity, also in the gas phase, and the interplay of hydrophobic and dispersive effects. Selected references: [1] K. I. Assaf, M. S. Ural, F. Pan, T. Georgiev, S. Simova, K. Rissanen, D. Gabel, W. M. Nau, Angew. Chem. Int. Ed. 2015, 54, 6852–6856. [2] K. I. Assaf, W. M. Nau, Chem. Soc. Rev. 2015, 44, 394–418. [3] M. Sayed, F. Biedermann, V. D. Uzunova, K. I. Assaf, A. C. Bhasikuttan, H. Pal, W. M. Nau, J. Mohanty, Chem. Eur. J. 2015, 21, 691–696. [4] F. Biedermann, W. M. Nau, H.-J. Schneider, Angew. Chem. Int. Ed. 2014, 53, 11158–11171. [5] G. Ghale, W. M. Nau, “Dynamically Analyte-Responsive Macrocyclic Host-Fluorophore Systems”, Acc. Chem. Res. 2014, 47, 2150–2159. [6] F. Biedermann, W. M. Nau, Angew. Chem. Int. Ed. 2014, 53, 5694–5699. [7] T.-C. Lee, E. Kalenius, A. I. Lazar, K. I. Assaf, N. Kuhnert, C. H. Grün, J. Jänis, O. A. Scherman, Werner M. Nau, Nature Chemistry 2013, 5, 376-382. [8] F. Biedermann, M. Vendruscolo, O. A. Scherman, A. De Simone, W. M. Nau, J. Am. Chem. Soc. 2013, 135, 14879−14888. [9] H. S. El-Sheshtawy, B. S. Bassil, K. I. Assaf, U. Kortz, W. M. Nau, J. Am. Chem. Soc. 2012, 134, 19935−19941. Biography: Werner Nau obtained his PhD at the University of Würzburg in 1994 with Waldemar Adam in organic chemistry. Following his postdoc at the University of Ottawa, Canada, in 1994/95 with J.C. “Tito” Scaiano in photochemistry, he completed his habilitation in physical chemistry with J. Wirz at the University of Basel, Switzerland, where he became Assistant Professor in 2000. Since 2002, he is Professor of Chemistry at Jacobs University Bremen, and, since 2011, Dean of the faculty. His research combines principles of organic photochemistry with optical spectroscopy and supramolecular chemistry and is directed towards applications in bioanalytical chemistry, peptide folding, drug delivery, drug discovery, catalysis, chiral recognition, fluorescent dye design, and enzyme assays.
This event is part of the eventgroup INT Talks
Speaker
Prof. Werner Nau

Jacobs University Bremen
http://wernernau.user.jacobs-university.de/?page_id=16
Organizer
Prof. Dr. Manfred Kappes
Institute of Nanotechnology (INT)
Karlsruhe Institute of Technology (KIT)
Eggenstein-Leopoldshafen
Mail: manfred kappes does-not-exist.kit edu
Targetgroup
Interested / Everyone
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