Massively parallel dip-pen nanolithography of heterogeneous supported phospholipid multilayer patterns

  • Author:

    S. Lenhert, P. Sun, Y. Wang, H. Fuchs, C. A. Mirkin 

  • Source:

    Small 3 (2007) 71-75 

  • Date: 2007
  • Drawing a parallel: The phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) can be used as an ink for noncovalent patterning on a variety of surfaces under humidity-controlled conditions. Simultaneous writing of different inks gives aligned, multilayer phospholipid patterns (see fluorescence image; scale bar=5 μm). These patterns are stable on some surfaces in water, while on others they can spread to form supported lipid bilayer membranes.