All-polymer chips with integrated optical waveguides and microfluidic channels were built as a platform for fluorescence excitation of biological samples. Their functionality has been shown for four cases: (i) fluorescence of labeled phospholipids inside a microfluidic channel, (ii) fluorescence of stained cells inside a microfluidic channel, (iii) fluorescence of labeled phospholipids on top of a polymer waveguide, and (iv) fluorescence of stained cells on top of a polymer waveguide.
Fluorescence excitation on monolithically integrated all-polymer chips
M. Schelb, C. Vannahme, A. Welle, S. Lenhert, B. Ross, T. Mappes
J. Biomed. Opt. 15 (2010) 041517