Site specific protein immobilization into structured polymer brushes prepared by AFM lithography
H. Wagner, Y. Li, M. Hirtz, L. Chi, H. Fuchs, A. Studer
Soft Matter 7 (2011) 9854-9858
- Date: 2011
Proteinimmobilization into structured polymerbrushes was achieved by AFM lithography. Dense polystyrenebrushes with thicknesses larger than 40 nm show proteinrepellent properties whereas brushes with thicknesses smaller than 20 nm show the expected known proteinadsorption behavior. Multi tip AFM lithographyallows for large surface area patterning.