Dip-Pen Nanolithography (DPN) and Related Techniques

Our group focuses on the advancement and application of dip-pen nanolithography and related techniques like polymer pen lithography (PPL) for the site-specific chemical and bio-chemical modification of surfaces and devices.
DPN GroupMichael Hirtz

Our Research Topics

Our research is aimed at the advancement and application of Scanning Proble Lithography (SPL) methods, in particular Dip-Pen Nanolithography (DPN) and related methods like e.g. Polymer Pen Lithography (PPL) and Microchannel Cantilever Spotting (µCS).

These SPL methods are versatile tools, combining many advantages of electron beam lithography, inkjet printing and microcontact printing in relation to resolution, integration and throughput. These methods are of particular interest when working with sensitive biological materials, since they work at mild process parameters and need no lift off processes (with the associated solvents or etching processes). Furthermore, the methods allows for "multiplexing", i.e. the parallel application of different inks within a pattern. Learn more about specific implementations and applications on our reseach page or browse our publications.


Liquid Metal Printed Electronics
Printed Electronics:

"High-Resolution Capillary Printing of Eutectic Gallium Alloys for Printed Electronics" by Hussain et al. in Adv. Mater. Technol. (2021) 2100650

Curvature sensitive protein screening
Lipid Membranes:

"Multiplexed phospholipid membrane platform for curvature sensitive protein screening" by Berganza Eguiarte et al. in Nanoscale (2021)

Cover for Cucurbituril Sensing
New Cover:

Chunting's paper on sensing with cucurbituril microarrays got a cover page! Congrats!

KNMFi Promo Video
KNMFi Relaunch:

New Video on the Karlsruhe Nano Micro Facility: "KNMFi Makes The Invisible Visible"

Epoxy Ring-Opening

"Protein Microarray Immobilization via Epoxide Ring‐Opening by Thiol, Amine, and Azide" by Dadfar et al. in Adv. Mater. Interfaces 8 (2021) 2002117

Curcubituril Arrays

"Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites" by Zhong et al. in ACS Appl. Nano Mater. 4 (2021) 4676-4687