INT | Scanning Probe Lithography

Dip-Pen Nanolithography (DPN) and Related Techniques

Our group focuses on the advancement and application of dip-pen nanolithography and related techniques like polymer pen lithography (PPL) for the site-specific chemical and bio-chemical modification of surfaces and devices.
DPN GroupMichael Hirtz

Our Research Topics

Our research is aimed at the advancement and application of Scanning Proble Lithography (SPL) methods, in particular Dip-Pen Nanolithography (DPN) and related methods like e.g. Polymer Pen Lithography (PPL) and Microchannel Cantilever Spotting (µCS).

These SPL methods are versatile tools, combining many advantages of electron beam lithography, inkjet printing and microcontact printing in relation to resolution, integration and throughput. These methods are of particular interest when working with sensitive biological materials, since they work at mild process parameters and need no lift off processes (with the associated solvents or etching processes). Furthermore, the methods allows for "multiplexing", i.e. the parallel application of different inks within a pattern. Learn more about specific implementations and applications on our reseach page or browse our publications.


Epoxy Ring-Opening

"Protein Microarray Immobilization via Epoxide Ring‐Opening by Thiol, Amine, and Azide" by Dadfar et al. in Adv. Mater. Interfaces 8 (2021) 2002117

Curcubituril Arrays

"Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites" by Zhong et al. in ACS Appl. Nano Mater. 4 (2021)

Wenwu Yang Wenwu Yang
New PhD Student:

We welcome our new PhD student Wenwu Yang! He will work on molecular sensor arrays in collaboration with the Biedermann group. We wish best success!

Controlled Surface Adhesion of Macrophages via Patterned Anti‐Fouling Polymer Brushes
Selective Cell Capture:

"Controlled Surface Adhesion of Macrophages via Patterned Anti‐Fouling Polymer Brushes" by Striebel et al. in Adv. NanoBiomed. Res. 1 (2021) 2000029

Best Thesis Award Johannes Striebel
Best Thesis Award:

Congratulations to Johannes Striebel, who was just award the iba Best Thesis Award for his master thesis!

Thioacetate‐Based Initiators for the Synthesis of Thiol‐End‐Functionalized Poly(2‐oxazoline)s
Functionalized Polymer Surfaces:

"Thioacetate‐Based Initiators for the Synthesis of Thiol‐End‐Functionalized Poly(2‐oxazoline)s" by Alvaradejo et al. in Macromol. Rapid Commun. 41 (2020) 2000320