Scanning Probe Lithography for Biomaterials and Bioelectronics

Our group focuses on the advancement and application of dip-pen nanolithography and related techniques like polymer pen lithography (PPL) for the site-specific chemical and bio-chemical modification of surfaces and devices.

The Scanning Probe Lithography for Biomaterials and Bioelectronics Group at INTOur research is aimed at the advancement and application of Scanning Probe Lithography (SPL) methods, in particular Dip-Pen Nanolithography (DPN) and related methods like e.g. Polymer Pen Lithography (PPL) and Microchannel Cantilever Spotting (µCS).

These SPL methods are versatile tools, combining many advantages of electron beam lithography, inkjet printing and microcontact printing in relation to resolution, integration and throughput. These methods are of particular interest when working with sensitive biological materials, since they work at mild process parameters and need no lift off processes (with the associated solvents or etching processes). Furthermore, the methods allows for "multiplexing", i.e. the parallel application of different inks within a pattern. Learn more about specific implementations and applications on our reseach page or browse our publications.


Microwriter Setup

"High-precision tabletop microplotter for flexible on-demand material deposition in printed electronics and device functionalization" by Hussain et al. in Rev. Sci. Instrum. 92 (2021) 125104

Scheme of Lipid Writing with FluidFM
Lipid Membranes:

"Direct-Write Patterning of Biomimetic Lipid Membranes In Situ with FluidFM" by Berganza et al. in ACS Appl. Mater. Interfaces 13 (2021) 50774–50784

Silver Star Ride
Group Outing:

No group members harmed during our outing to the Europa-Park! ;-D

Scheme of extracellular vesicles capture on lipid membranes
Cancer Diagnostics:

"Rapid Capture of Cancer Extracellular Vesicles by Lipid Patch Microarrays" by Hui et al. in Adv. Mater. 33 (2021) 2008493

Liquid Metal Printed Electronics
Printed Electronics:

"High-Resolution Capillary Printing of Eutectic Gallium Alloys for Printed Electronics" by Hussain et al. in Adv. Mater. Technol. 6 (2021) 2100650

Curvature sensitive protein screening
Lipid Membranes:

"Multiplexed phospholipid membrane platform for curvature sensitive protein screening" by Berganza et al. in Nanoscale 13 (2021) 12642-12650